Papillomavirus self-assembling

Papillomavirus icosahedral capsid self-assembly

Papillomavirus icosahedral capsid self-assembly



Papillomaviridae is an ancient taxonomic family of non-enveloped DNA viruses. A single viral protein, known as L1, is necessary and sufficient for formation of a 60 nanometer capsid composed of 72 star-shaped capsomers (see figure). Like most non-enveloped viruses, the capsid is geometrically regular and presents icosahedral symmetry. Self-assembled virus-like particles composed of L1 are the basis of a successful group of prophylactic HPV vaccines designed to elicit virus-neutralizing antibodies that protect against initial HPV infection.

2 thoughts on “Papillomavirus self-assembling

  1. Hello, We would like to obtain permission to use the above image in a educational website created at Stanford University for non-commercial use. Our website is : http://genderedinnovations.stanford.edu and we would like to use it on our HPV page about using Nanotechnology screening for HPV prevention. Thank you very much!
    Rosemary Rogers
    web dsigner
    Stanford University

  2. Hello, could you tell me please is it possible to buy this photo for using in illustated russian journal about hpv? Kind regards Dmitry/

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