Flu M2 membrane ion channel 3d structure block by adamantanes.

Flu virus surface proteins, M2 in blue, target of adamantane viral drugs in orange. M2 proton channel allows acid to enter the virus triggering the release of its genetic instructions. Adamantane antivirals, such as amantadine and rimantidine, inactivate M2 and thus stop the virus proliferation.

Flu virus surface proteins, M2 in blue, target of adamantane viral drugs in orange. M2 proton channel allows acid to enter the virus triggering the release of its genetic instructions. Adamantane antivirals, such as amantadine and rimantidine, inactivate M2 and thus stop the virus proliferation.

One thought on “Flu M2 membrane ion channel 3d structure block by adamantanes.

  1. This image ignores substantial, if not the preponreance of evidence, that the adamantane-type antivirals targeting the M2 channel of influenza type A viruses do so by entering **within** the channel, rather than bindng its periphery (as shown, whose proponents in the M2 area are largely limited to Chou et al. of the HMS).

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